Pressure ulcer. Decubitus ulcer and pressure area, unspecified
Conditions
Interventions
Intervention 1: Intervention: local application of Phenytoin cream 1% once daily in areas susceptible to ulcer (sacrum
iliac
spinal cord
waist
shoulder
auricle
buttock
heel and ankle) to the extent that cover the wound area and local application of Q. infectoria gall extract in the cream tube that is similar to placebo at 12 hours later for two weeks. Intervention 2
heel and ankle) to the extent that cover the wound area and local application of placebo in the cream tube that is similar to drug at 12 hours later for two weeks.
Treatment - Drugs
Placebo
Intervention: local application of Phenytoin cream 1% once daily in areas susceptible to ulcer (sacrum
Sponsors
Vice-chancellor for Research and Technology, Hamadan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
37 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with 2/5 or more of paralysis due one-way stroke and with pressure ulcer; patients who score 16 or less in Norton scale. Exclusion criteria: patient death or transfer to another health center; patient with necrotic wound due pressure ulcer at the beginning of the study; positive response to allergy test of Q. infectoria gall extract; progression of pressure ulcer to higher grades during the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grade of pressure ulcer. Timepoint: At baseline and then daily for two weeks. Method of measurement: Through physical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessing local reactions such as rash, hives, or redness. Timepoint: 24 hours later. Method of measurement: Through physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDara Dastan
School of Pharmacy
Outcome results
None listed