Gastric Helicobacter pylori infection eradication rate with levofloxacin based regimen and comparison with standard clarithromycin regimen

Evaluation of H pylori eradication rate with 14-days levofloxacin,amoxicillin&pantoprazole regimen and its comparison with standard regimen of clarithromycin,amoxicillin &pantoprazole in patients of gastrointestinal clinic

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170803035490N1

Enrollment

170

Registered

2017-12-04

Start date

2017-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters

Interventions

Intervention 1: Levofloxacin:250 mg po Bid , Amoxicillin:1 gr po Bid, Pantoprazole:40 mg po Bid 14 days. Intervention 2: Clarithromycin:500 mg po Bid , Amoxicillin:1gr po Bid , Pantoprazole

Treatment - Drugs

Levofloxacin:250 mg po Bid , Amoxicillin:1 gr po Bid, Pantoprazole:40 mg po Bid 14 days

Clarithromycin:500 mg po Bid , Amoxicillin:1gr po Bid , Pantoprazole :40 mg po Bid , 14 days

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age from 18 to 65 yrs With epigastric problems

Exclusion criteria

Exclusion criteria: PPI consumption in 2 wks ago Antibiotic use in 4 wks ago GI bleeding Allergy to antibiotics Drug intolerance Unresponsiveness to standard clarithromycin regimen( duo to ethic consideration)

Design outcomes

Primary

Measure	Time frame
Helicobacter pylori eradication rate in stomach. Timepoint: One month after therapy. Method of measurement: Stool antigen test.	—

Secondary

Measure	Time frame
Drug side effects. Timepoint: during and after intervention. Method of measurement: monitoring for side effects.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Bijan Ahmadi

Kerman University of Medical Sciences

Ay_bijan@yahoo.com+98 34 3132 8000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026