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The Effect of Ondansetron, Vitamin B6 and Rhizome in Nausea and Vomiting of Pregnancy in pregnant women referred to health centers in Hamadan city

The Effect of Ondansetron, Vitamin B6 and Rhizome in Nausea and Vomiting of Pregnancy in pregnant women referred to health centers in Hamadan city

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201708026888N19
Enrollment
120
Registered
2017-08-19
Start date
2017-08-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and Vomiting during pregnancy. Hyperemesis gravidarum, mild or unspecified, starting before the end of the 22nd week of gestation

Interventions

Intervention 1: Intervention group: The participants will randomly select to one of four oral treatments groups for one week : Ondansetron (4 mg/twice a day), and Rhizome (250 mg/twice a day) or Vitam
Treatment - Drugs
Placebo
Intervention group: The participants will randomly select to one of four oral treatments groups for one week : Ondansetron (4 mg/twice a day), and Rhizome (250 mg/twice a day) or Vitamin B6 (40 mg/twi
Control group: Prescription Placebo twice a day for one week.

Sponsors

Vice Chancellor for Research and Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age of 18-40 years; Primi Para; No history of psychological illness; non-use of psychological drugs. exclusion criteria: Unwillingness to continue cooperation; Allergy to drug useage.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Nausea and vomiting. Timepoint: Before the intervention and one week after the intervention. Method of measurement: PUQE-24 questionnaire.

Secondary

MeasureTime frame
Severity of nausea and vomiting. Timepoint: Before the intervention, and one week after the intervention. Method of measurement: PUQE-24 questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Shobeiri

Hamadan University of Medical Sciences

shobeiri@umsha.ac.ir+98 81 3827 6051

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026