Kienböck disease of adults. Adult osteochondrosis of carpal lunate
Conditions
Interventions
Deferoxamine, 500mg, two sessions, once at the start of the study and once two weeks later..
Treatment - Drugs
Deferoxamine, 500mg, two sessions, once at the start of the study and once two weeks later.
Sponsors
Vice Chancellor for research of Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Radiologic Diagnosis of the Kienbock's disease by 3 hand surgeons; Age of 18 to 60 years. Lack of hematologic disorders and any disease with platelet Dysfunction; Lack of any comorbid disorders that might increase the risk of surgery including uncontrolled diabetes, cardiovascular disorders, rheumatic diseases such as rheumatoid arthritis, cancers, hepatic and renal failure and etc; Consumption of no drug which affect bone restoration such as corticosteroids. Exclusion Criteria: New severe trauma affecting the fracture dislocation and fixation status, Incidence of severe infection which can not be controlled with antibiotics and needs surgery; Incidence of disorders needing specific drugs such as corticosteroids and chemotherapy which affect the bone repair.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical and radiologic symptoms. Timepoint: Months 3, 6 and 12 of intervention. Method of measurement: Range of Motion, Xray and MRI. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactfarid Najd Mazhar
Shafa Orthopedic Hospital
Outcome results
None listed