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The effect of low dose aspirin on platelet inhibition in patients with rheumatoid arthritis

The effect of low dose aspirin on platelet inhibition in patients with rheumatoid arthritis

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT201707293812N6
Enrollment
45
Registered
2017-08-08
Start date
2017-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Rheumatoid arthritis. Condition 2: Rheumatoid arthritis. Rheumatoid arthritis, unspecified Rheumatoid arthritis, unspecified

Interventions

Prescribing 80 mg of asprin on the patient's group and taking the drug for one week.After the last dose and re sampling, blood samples will be used to measure serum TX levels.
Treatment - Drugs
Prescribing 80 mg of asprin on the patient's group and taking the drug for one week.After the last dose and re sampling, blood samples will be used to measure serum TX levels

Sponsors

Connective Tissue research Center- Tabriz University of Medical Sciences
Lead Sponsor
abriz University of Medical Sciences, Tabriz, Iran
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with rheumatoid arthritis who have been diagnosed with EULAR 2010 ACR criteria and have been ill for 6 months Exclusion criteria: Includes recent use of aspirin and anti-coagulant drugs, history of aspirin allergy, renal failure (creatinine above 8.1 mg / dL), thrombotic cytopenia, pregnancy, gastric ulcer and gastrointestinal bleeding. Patients with maternal and metabolic disorders are also among the exclusion criteria.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Platelet aggregation. Timepoint: One week. Method of measurement: Elisa.

Secondary

MeasureTime frame
TXA2. Timepoint: one weak. Method of measurement: Elisa.;TX-A2. Timepoint: One week. Method of measurement: Elisa.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir ghorbanihaghjo

Tabriz University of Medical Sciences

ghorbaniamir@hotmail.com+98 41 3336 4666

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026