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Effect of of escitalopram and relaxation on hot flashes of patients with breast cancer

A comparative study of escitalopram ,placebo and relaxation on hot flashes of patients with breast cancer

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017072834482N2
Enrollment
87
Registered
2017-08-22
Start date
2017-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hot Flash. Menopausal and female climacteric states

Interventions

Intervention 1: Intervention group: Escitalopram tab 10mg one time a day for 4 weeks. Intervention 2: control group:Placebo tab one time a day for 4 weeks. Intervention 3: Intervention group: relaxati
Treatment - Drugs
Placebo
Behavior
Intervention group: Escitalopram tab 10mg one time a day for 4 weeks
Intervention group: relaxation methods at least 30 minutes one time a day for 4 weeks

Sponsors

Vice chancellor for Research, Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: having at least 4 hot flash attacks daily; Age range is 18 to 65 years; a history of breast cancer; not in acute phase of breast cancer, Ability to read and write and being able to answer questions ;Consent to participate in the study; Not concurrent using of any drugs that affect hot flash symptoms such as gabapentin, pregabalin, clonidine, SSRIs, herbal drugs and other treatments such as acupuncture, hypnotism ; no Non-malignant hypertension or CVA or MI or other uncontrolled organic problems and psychotic or bipolar disorders Exclusion criteria: incidence of intolerable drug side effects, breast cancer relapse needing chemotherapy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hotflash frequency. Timepoint: before treatment and 4 weeks after treatment. Method of measurement: Hotflash diary.

Secondary

MeasureTime frame
Hotflash duration. Timepoint: before treatment and 4 weeks after treatment. Method of measurement: Hotflash diary.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Maryam Shirzadi

Kermanshah University Of Medical Science

m_shirzadi@kums.ac.ir+98 83 3427 6310

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026