Vitamin D supplementation effect on cyclical mastalgia

Evaluation of the effect of Vitamin D supplementation on pain and serum level of prolactin in women suffering from cyclical mastalgia

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017072610327N16

Enrollment

Registered

2017-08-26

Start date

2017-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cyclical mastalgia. Mastodynia

Interventions

Intervention 1: Intervention group: This group will receive 2000 IU of oral vitamin D per day for 8 weeks. Intervention 2: Control group: The control group will receive placebo for 8 weeks.

Placebo

Intervention group: This group will receive 2000 IU of oral vitamin D per day for 8 weeks.

Control group: The control group will receive placebo for 8 weeks.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: At least 18 years of age; serum level of vitamin D 10- 30 ng/ ml; breast pain duration of =5 days per menstrual cycle; without any somatic or psychological disease. Exclusion criteria : Pregnant or lactating women; history of breast cancer; Stressful life events such as death of a family member.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Intensity of mastalgia. Timepoint: before and after intervention. Method of measurement: Visual analogue scale (VAS).;Serum level of prolactin. Timepoint: before and after intervention. Method of measurement: Lab test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarideh Vaziri

Shiraz University of Medical Sciences

roose82003@yahoo.com; vazirif@sums.ac.ir+98 71136281497

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026