Diabetic patients with Vitamin D Defficiency. diabetes (mellitus)(nonobese)(obese),Vitamin D deficiency, unspecified
Conditions
Interventions
Intervention 1: "Intervention group': Vitamin D supplementation(50000 IU/Week). Intervention 2: "Control group": placebo (1 capsule of corn oil same in shape, weight, color, and size with intervention
Treatment - Drugs
Placebo
"Intervention group': Vitamin D supplementation(50000 IU/Week)
"Control group": placebo (1 capsule of corn oil same in shape, weight, color, and size with intervention supplement weekly)
Sponsors
Shiraz University Of Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Criteria for entering the study: Willingness to participate; Prior diagnosis of type 2 diabetes by a specialist; Minimum duration of 2 years diagnosis; No Smoking or Drug abuse; No weight changes over the past 6 months (based on self report); The fixed type and dose of medications used in the last 6 months; Not having severe heart disease, stroke, liver disease, kidney, gastrointestinal, thyroid and parathyroid, rheumatoid arthritis and infectious diseases; Not using any supplements whether containing vitamin D and calcium or anti-oxidant supplements in the last 6 months; Absence of pregnancy or lactation Exit criteria: Misdiagnosis of demographic or anthropometric information; Failure to follow the design of the study (consuming less than 90% of supplements or not taking supplements for more than three consecutive periods); Unusual biochemical specimen; Use of any supplements other than the supplement provided in the study; Use of Venostat (orlistat)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TG. Timepoint: before and after 8 weeks of intervention. Method of measurement: Standard Enzymatic Method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fbs. Timepoint: before and after 8 weeks of intervention. Method of measurement: Standard Enzymatic Method.;Serum vitamin D level. Timepoint: before and after 8 weeks of intervention. Method of measurement: Standard Enzymatic Method.;Net Weight Changes. Timepoint: before and after 8 weeks of intervention. Method of measurement: Scales.;Waist circumference changes. Timepoint: before and after 8 weeks of intervention. Method of measurement: By flexible stata meter (at highest level of circumference).;Glycated Hemoglubin. Timepoint: before and after 8 weeks of intervention. Method of measurement: Via standard labratory method (RIA).;TG. Timepoint: before and after 8 weeks of intervention. Method of measurement: Standard Enzymatic Method.;TC. Timepoint: before and after 8 weeks of intervention. Method of measurement: Standard Enzymatic Method.;LDL. Timepoint: before and after 8 weeks of intervention. Method of measurement: Standard Enzymatic Method.;HDL. Timepoint: before and after 8 weeks of intervention. Method of measurement: Standard Enzymatic Method.;MAD. Timepoint: before and after 8 weeks of intervention. Method of measurement: Standard Enzymatic Method.;HsCRP. Timepoint: before and after 8 weeks of intervention. Method of measurement: ELISA kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSahar Shahriari
Departman of Clinical Nutrition, School of Nutrionand Food sciences, Shiraz university of medical Sc
Outcome results
None listed