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Evaluating the effect of vitamin E in patients with a history of renal stone

Evaluating the effect of vitamin E on 24-hour urine oxalate and citrate in patients with a history of renal stone

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170725035305N5
Enrollment
60
Registered
2021-04-09
Start date
2021-04-21
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with kidney stones. Calculus of kidney

Interventions

Intervention 1: Intervention group: The intervention group (n = 30) received a pearl 400 IU vit E and standard treatment based on urine metabolic evaluation for 8 weeks. Intervention 2: Control group

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age 18-65 years Literate history of renal stone

Exclusion criteria

Exclusion criteria: primary hyperoxaluria ( urine 24 h oxalate more than 80 mg/24 h ) or enteric hyperoxaluria changing the dose or initiating potassium citrate during study use of drugs with any effect on oxalate eg B6 Patients with diabetes, Hypertension or renal disease pregnancy and lactation history of cystinuria history of Inflamatory bowel disease history of hyperparathyroidism use of vitamin supplement or anti oxidants use of warfarin unwillingness

Design outcomes

Primary

MeasureTime frame
24-hour urine citrate. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.;24-hour urine oxalate. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.

Secondary

MeasureTime frame
Serum Uric acid level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum calcium level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhesam Alirezaei

Shahid Beheshti University of Medical Sciences

amirhesam124@gmail.com+212 2083112

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026