The effects of Portulaca Oleracea extract on thirsty and 24 hour urine indices

The effects of Portulaca Oleracea extract on thirsty and 24 hour urine indices in patients with renal stone: a double-blind randomized placebo-controlled clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170725035305N4

Enrollment

Registered

2020-05-02

Start date

2020-07-22

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with kidney stones. Calculus of kidney and ureter

Interventions

Intervention 1: Intervention group: The intervention group (n = 30) received a capsul containing of 2 grams Portulaca Oleracea hydro alcoholic extract and half a gram of brown sugar should be taken w

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age 18-65 years Literate

Exclusion criteria

Exclusion criteria: Patients with diabetes Oral problems No use of angiotensin II inhibitors Patients with colds

Design outcomes

Primary

Measure	Time frame
Serum Potassium level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum Sodium level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;24-hour urine uric acid. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.;24-hour urine citrate. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.;Specific weight of urine. Timepoint: At the start of the study and at the end of the study. Method of measurement: Urine sample.;24 hour urine calcium. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.;24-hour urine creatinine. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.;24-hour urine Na. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.	—

Measure

Time frame

Serum Potassium level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum Sodium level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;24-hour urine uric acid. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.;24-hour urine citrate. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.;Specific weight of urine. Timepoint: At the start of the study and at the end of the study. Method of measurement: Urine sample.;24 hour urine calcium. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.;24-hour urine creatinine. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.;24-hour urine Na. Timepoint: At the start of the study and at the end of the study. Method of measurement: 24 h Urine collection.

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Secondary

Measure	Time frame
Thirst intensity. Timepoint: At the start of the study, at the end of the study. Method of measurement: using Visual Analogue Scale.;Serum triglycerid level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum cholestrol level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum HDL level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Total antioxidant level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;ESR. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;CRP. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum Uric acid level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum Creatinine level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum Urea level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum calcium level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Venous blood gas. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.	—

Measure

Time frame

Thirst intensity. Timepoint: At the start of the study, at the end of the study. Method of measurement: using Visual Analogue Scale.;Serum triglycerid level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum cholestrol level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum HDL level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Total antioxidant level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;ESR. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;CRP. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum Uric acid level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum Creatinine level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum Urea level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Serum calcium level. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.;Venous blood gas. Timepoint: At the start of the study and at the end of the study. Method of measurement: blood sample.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhesam Alirezaei

Shahid Beheshti University of Medical Sciences

amirhesam124@gmail.com+212 2083112

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 8, 2026