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Efficacy of oral administration of Allium sativum on lipid profile, inflammatory and cardiovascular indexes among hemodialysis patients

Effectiveness of oral administration of Allium sativum on lipid profile, inflammatory and cardiovascular indexes among hemodialysis patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170725035305N2
Enrollment
60
Registered
2018-01-21
Start date
2018-01-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Hemodyalisis. Dependence on renal dialysis

Interventions

Intervention 1: Intervention group: In the intervention group, patients received 400 mg of standard garlic powder extract tablets twice aday for 8 weeks. each tablet contains 1000 micrograms of allii
Treatment - Drugs
Placebo
Intervention group: In the intervention group, patients received 400 mg of standard garlic powder extract tablets twice aday for 8 weeks. each tablet contains 1000 micrograms of alliin. The drug was
Control group: The placebo was prescribed. The placebo was completely similar to the original drug and it was made of starch. Patients will receive placebo tablets twice a day for 8 weeks. The drug wa

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years 6 month after initiation of hemodialysis

Exclusion criteria

Exclusion criteria: Recent use of medicines and foods that contain garlic Sensitivity to garlic History of bleeding History of infection or hospitalization in the past 3 month History of warfarin use History of ileal bypass

Design outcomes

Primary

MeasureTime frame
Lipid profile. Timepoint: Before and after intervention. Method of measurement: Laboratory measurement.;IL6. Timepoint: Before and after intervention. Method of measurement: Laboratory measurement.;ESR. Timepoint: Before and after intervention. Method of measurement: Laboratory.;Homocysteine. Timepoint: Before and after intervention. Method of measurement: Laboratory measurement.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhesam Alirezaei

Shahid Beheshti University of Medical Sciences

Amirhesam124@gmail.com+98 21 2207 4101

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026