The effect of sublingual misoprostol and Foley catheter on termination of pregnancy

Evaluation of the results of using 25 µg sublingual misoprostol and Foley catheter together and each one alone in preparing cervix in low-term term pregnancies for termination of pregnancy with less than 4

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017072326695N2

Enrollment

Registered

2017-07-31

Start date

2017-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delivery. delivery

Interventions

Intervention 1: Group I: Sublingual misoprostol (25 µg). Intervention 2: Group III: Foley catheter with 30 ml normal saline. Intervention 3: Group II: Sublingual misoprostol 25 µg and foley catheter (

Group I: Sublingual misoprostol (25 µg)

Group III: Foley catheter with 30 ml normal saline

Group II: Sublingual misoprostol 25 µg and foley catheter (30 ml normal saline) simultaneously

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Pregnant women who indicate a termination of pregnancy (37-42 weeks); have normal delivery conditions: Cephalic presentation; women aged 18-45; urine score less than 4 Exclusion criteria: Abnormal heartbeat; Vaginal bleeding; Placenta praevia & Placental abruption; Multiple birth; Non-Cephalic presentation & Macrosomia; Infertility history greater than or equal to 6 years old and abnormal or fetal death; Multi-frequency higher than most 7; Rupture of Membeans; Intrauterine growth restriction and weighing over 4000 grams; History of uterine surgeries; tachycardia in mother; Preeclampsia; Abnormal liver and kidney tests

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Termination of pregnancy. Timepoint: Before intervention, 6 hours after intervention, 12 hours after intervention, 18 hours after intervention. Method of measurement: The amount of contractions of the womb.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Leila Khayat zonuzi

Yas Hospital

l.zonuzi@zaums.ac.ir+98 21 8889 7761

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026