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Evaluation of Palem topical preparation on psoriasis

Comparison of Sambucus ebulus topical preparation and placebo, on skin disorders in psoriasis patients, a clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017072210203N8
Enrollment
60
Registered
2017-07-24
Start date
2016-06-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis. Generalized pustular psoriasis

Interventions

Intervention 1: Intervention group: Sambucus ebulus topical preparation 2% (ointment) formulated in Sari"s faculty of pharmacy, two times a day for two months. Intervention 2: Control group: Placebo (
Treatment - Drugs
Placebo
Intervention group: Sambucus ebulus topical preparation 2% (ointment) formulated in Sari"s faculty of pharmacy, two times a day for two months
Control group: Placebo (ointment without extract), two times a day for two months

Sponsors

Vice chancellor for research, Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
13 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Patients with psoriasis during 3 months, at the age of 13 years and more; 3 times pruritus during last two weeks before study; or receive treatment during one month without any significant response. Exclusion criteria: pregnancy and breast feeding; sensitivity to topical preparation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Pruritus. Timepoint: time zero, and after 4 and 8 weeks. Method of measurement: qualitative questioner (0 to 4).

Primary

MeasureTime frame
PASI Score. Timepoint: Time zero and after 4 and 8 weeks. Method of measurement: Based on area (head, trunk, arms, legs) and erythema, induration and scaling by physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Saeedi

Mazandaran University of Medical Sciences

majsaeedi@gmail.com+98 11 3354 3082

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026