evaluation of Curcuma tablet efficacy in nonalcoholic fatty liver patients

Evaluation of curcuma (turmeric) efficacy on biochemical and liver sonography criteria in non-alcoholic fatty liver patients

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170722035222N2

Enrollment

100

Registered

2018-04-18

Start date

2017-09-23

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nonalcoholic fatty liver. Fatty (change of) liver, not elsewhere classified

Interventions

Intervention 1: Intervention group: Patients in this group are treated with one 20 mg Curcuma tablet (Dina Company) for 8 weeks. Intervention 2: Control group: Patients in the control group receive on

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: patients who diagnosed as NAFLT with examination, liver function tests, sonography, history taking and high AST ALT age 30-65 year sign up the testimonial

Exclusion criteria

Exclusion criteria: smoking or drug abuse diabetes alcoholic viral hepatitis infection disease cirrhosis history of using hepatotoxic drugs such as methotrexate, amiodarone, valproic acid, anabolic steroid, estrogen, glucocorticoids and ... being pregnant or lactating hypotension

Design outcomes

Primary

Measure	Time frame
AST. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: Serum per liter in biochemical tests.;ALT. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: Serum per liter in biochemical tests.;Liver sonography. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: Assessing the grade of fatty liver based on the accumulation of fatty vacuoles in liver cells.	—

Measure

Time frame

AST. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: Serum per liter in biochemical tests.;ALT. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: Serum per liter in biochemical tests.;Liver sonography. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: Assessing the grade of fatty liver based on the accumulation of fatty vacuoles in liver cells.

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Secondary

Measure	Time frame
BMI. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: In kilograms per meter using the BMA calculation formula.;FBS. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: In mg per deciliter in biochemical tests.;Weight. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: In kilograms using digital scales.	—

Measure

Time frame

BMI. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: In kilograms per meter using the BMA calculation formula.;FBS. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: In mg per deciliter in biochemical tests.;Weight. Timepoint: Before intervention and 8 weeks after drug therapy. Method of measurement: In kilograms using digital scales.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Arash Hedayat

Esfahan University of Medical Sciences

arash.hedayat1988@gmail.com+98 31 3625 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026