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Dapson in acne vulgaris

Comparison of the efficacy of dapsone 5% gel plus oral doxycycline versus benzoyl peroxide 5% gel plus oral doxycycline in patients with moderate acne vulgaris

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017072035195N1
Enrollment
60
Registered
2017-10-23
Start date
2017-08-23
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

Intervention 1: In control group , benzoyl peroxide 5% Gel once daily for 3 months is adminestrated. Intervention 2: In cases group , Dapson 5% Gel once daily for 3 months is adminestrated.

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Patients with acne vulgaris who have 15-50 inflammatory lesions and 20-100 non-inflammatory lesions (comedones) (ranked as moderate in the GASS classification). The total number of lesions accounts for 30 to 120 (ranked as moderate in the GASS classification).

Exclusion criteria

Exclusion criteria: Secondary acne due to other diseases or causes Using other oral or topical medicines to treat acne G6PD deficiency Severe nodular cystic acne (ranked as very severe in the GASS classification) Acne conglobata.

Design outcomes

Primary

MeasureTime frame
Inflammatory lesion (papule & pustule) non inflammatory (comedone). Timepoint: weeks 2, 4, 8, 12 after treatment. Method of measurement: GAAS Score.

Secondary

MeasureTime frame
Side effects (Erythem, Burning, pruritus, Skin dryness, phototoxicity). Timepoint: weeks 2 , 4 , 8 , 12 after treatment. Method of measurement: History and examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hojat Eftekhari

Guilan University of Medical Sciences

EFTEKHARI@GUMS.AC.IR+98 13 3355 0028

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026