Surgical Site Infection. -
Conditions
Interventions
Intervention 1: Intervention group 1: Received amp cefazolin 1 gr Iv q 6 hours for 48 h and then cap cephalexin 500 mg q 6 hours for 5 days (Farabi pharmaceutical company). Intervention 2: Intervent
Treatment - Drugs
Intervention group 1: Received amp cefazolin 1 gr Iv q 6 hours for 48 h and then cap cephalexin 500 mg q 6 hours for 5 days (Farabi pharmaceutical company).
Intervention group 2: Received amp cefazolin 1 gr Iv q 6 hours for 48 h and then placebo q 6 hours for 5 days (Farabi pharmaceutical company).
Sponsors
Vice-chancellor Of Research Babol University Of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : All patients with indication of CABG Exclusion criteria : Patients > 80 and 6 hours or duration of Pomp time more >120 minutes or aorta clumping time > 60 minutes; insertion of intra aortic ballon pupm; use high dose of inotropes; Emergent surgery; The presence of Comorbidities (e.g. liver failure , renal failure (serum cratinine > 2).
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infection rate. Timepoint: 48h after the surgery, 7-10 days after the surgery, 30 days after the surgery. Method of measurement: Wound observation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Responsible pathogens for infection. Timepoint: -. Method of measurement: Wound secretion culture.;Drug resistance. Timepoint: -. Method of measurement: Antibiogram. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMostafa Javanian
Babol University Of Medical Sciences
Outcome results
None listed