hand-foot syndrome. localized skin eruption due to drugs and medicaments
Conditions
Interventions
Intervention 1: The topical nano-tretinoin will be administrated to hands and feet of patients once or twice daily for 1 to 3 months Based on patients' response. Intervention 2: The topical placebo wi
Treatment - Drugs
Placebo
The topical nano-tretinoin will be administrated to hands and feet of patients once or twice daily for 1 to 3 months Based on patients' response.
The topical placebo will be administrated to hands and feet of patients once or twice daily for 1 to 3 months Based on patients' response.
Sponsors
Pharmaceutical Sciences branch, Islamic Azad University(a part of hanieh pourmousavi's PharmD thesis
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients with hand-foot syndrome; Patients who 30 to 80 years old. Exclusion criteria: Skin infections; Skin cancer; Sensitivity to compounds of formula; Patient dissatisfaction
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of hand-foot syndrome. Timepoint: Beginning of the study, every 14 days, End of the study. Method of measurement: Common Terminology Criteria for Adverse Events. | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin Sensitivity. Timepoint: Beginning of the study, every 14 days, End of the study. Method of measurement: Observational. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHanieh pourmousavi
islamic Azad University Of Pharmaceutical Sciences Branch
Outcome results
None listed