Pain intensity after deep vitrectomy. Other specified postprocedural states
Conditions
Interventions
Intervention 1: The first intervention group will receive 0.1 mg/kg of metoclopramide by intravenous infusion for ten minutes, 15 minutes before the end of surgery. Intervention 2: The second interven
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients undergoing pars plana deep vitrectomy (20G) surgery Age between 18 to 75 years Status classification I or II according to the American Society of Anesthesiologists (ASA) Status Classification System Body mass index (BMI) less than 35 Ability to speak Written informed consent
Exclusion criteria
Exclusion criteria: History of taking corticosteroids and immunosuppressants since one month before surgery History of allergies to metoclopramide or aminophylline, Taking metoclopramide, aminophylline, or any other analgesics 24 or less than 24 hours before surgery, History of malignancy, uncontrolled diabetes, smoking cigarettes, addictive drugs, and alcohol abuse, chronic pain for more than six months, mental illness, evident preoperative anxiety or tachycardia, history of taking anti-anxiety or anti-arrhythmic medications, and a history of general anesthesia by using volatile anesthetics, in the last six months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient's post-operative pain intensity. Timepoint: At the beginning of admission at the recovery ward, then at 30 and 60 minutes and 2, 4, 8, 16, and 24 hours after entering the recovery ward. Method of measurement: The Visual Analog Scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean of blood pressure (mm Hg). Timepoint: During surgery (once), in the recovery ward, and 8 hours after the surgery. Method of measurement: Clinical mercury manometer.;Heart rate (beats per minute). Timepoint: During surgery (once), in the recovery ward, and 8 hours after the surgery. Method of measurement: Beat count by palpating distal radius pulse.;Respiratory rate (breaths per minute). Timepoint: During surgery (once), in the recovery ward, and 8 hours after the surgery. Method of measurement: Capnometry.;Pethidine required for sedation. Timepoint: Whenever the visual analog scale scores more than 3. Method of measurement: It is measured by counting the number of pethidine injections up to the end of 24 hours after admission to the recovery ward.;The patients’ satisfaction status. Timepoint: Until the end of 24 hours after entering the recovery ward. Method of measurement: Questionnaire (completely satisfied, relatively satisfied, relatively dissatisfied, and completely dissatisfied).;Recovery time. Timepoint: Until the end of 24 hours after entering the recovery ward. Method of measurement: Timer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDaroush Moradi Farsani
Esfahan University of Medical Sciences
Outcome results
None listed