Craniotomy. Cranial nerve disorder, unspecified
Conditions
Interventions
Intervention 1: After the completion of the surgery, the intervention group will receive a dose of 1 microgram per kilogram of body weight diluted in a volume of 20 ml for 10 minutes and a repeated do
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age between 20 and 80 years Candidate for craniotomy Intubation of patients after surgery Being under mechanical ventilation for up to 24 hours Patient consent to participate in the study
Exclusion criteria
Exclusion criteria: Surgical time shorter than 30 minutes Cardiac arrest Drug allergy Third-degree atrioventricular block A heart rate below 45 per minute Systolic pressure below 80 mmHg Not consenting to take part in the study Unavailability of the patient or the inability to follow the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation score based on Richmond Agitation Sedation scale. Timepoint: In the 30th minute and 4th, 8th, 12th, 16th, 20th and 24th hour after the patient's admission to the recovery. Method of measurement: Richmond Agitation Sedation scale.;Complications due to Dexmedetomidine intake. Timepoint: In the 30th minute and 4th, 8th, 12th, 16th, 20th and 24th hour after the patient's admission to the recovery and until the discharge of the patient. Method of measurement: Questionnaire.;The satisfaction of the patient's nurse according to the Visual Analogue Scale. Timepoint: After the completion of the surgery and before entering the recovery. Method of measurement: The Visual Analogue Scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic blood pressure (mm Hg). Timepoint: In the 30th minute and 4th, 8th, 12th, 16th, 20th and 24th hour after the patient's admission to the recovery. Method of measurement: Clinical mercury manometer.;Diastolic blood pressure (mm Hg). Timepoint: In the 30th minute and 4th, 8th, 12th, 16th, 20th and 24th hour after the patient's admission to the recovery. Method of measurement: Clinical mercury manometer.;Heart rate (beats per minute). Timepoint: In the 30th minute and 4th, 8th, 12th, 16th, 20th and 24th hour after the patient's admission to the recovery. Method of measurement: Beat count by palpating distal radius pulse.;Peripheral capillary oxygen saturation (percentage). Timepoint: In the 30th minute and 4th, 8th, 12th, 16th, 20th and 24th hour after the patient's admission to the recovery. Method of measurement: Pulse oximetry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Taghi Hashemi
Esfahan University of Medical Sciences
Outcome results
None listed