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Comparison of the efficiency and side effects of morphine and diclofenac suppositories with intramuscular pethedine in controlling post operative pain in appendectomy and inguinal hernia

Comparison of the efficiency and side effects of morphine and diclofenac suppositories with intramuscular pethedine in controlling post operative pain in appendectomy and inguinal hernia

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017071134841N2
Enrollment
75
Registered
2017-09-02
Start date
2013-03-27
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: postoperative pain control in appendectomy. Condition 2: postoperative pain control in inguinal hernia. Diseases of appendix Inguinal hernia

Interventions

Intervention 1: In the first group, suppository morphine 10 mg was administered at hours 2 nd, 6th, 12th and 24th after surgery. Intervention 2: In the second group, diclofenac suppository was given 1
Treatment - Drugs
In the first group, suppository morphine 10 mg was administered at hours 2 nd, 6th, 12th and 24th after surgery.
In the second group, diclofenac suppository was given 100 mg at 2 nd, 6th, 12th, and 24th hours after surgery.
In the control group or the third group, if the patient had postoperative pain and the patient had a pain score above 4, 50 mg intramusclar pethidine was used to control pain.

Sponsors

Deputy Research of Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients underwent appendectomy and inguinal hernia in the age group of 18-70 years. Pregnant women, patients with neurological disease or psychiatric disorders, with history of seizure, with acute or chronic kidney disease, history of gastrointestinal ulcer, drug users Psychotropic substances users or alchohol consumption and those with hemorrhoids or anus disorder were not included in the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: In the hours 2,6,12,24 after surgery. Method of measurement: To measure the final outcome of the study patient pain score was based on the visual analogue score criteria with metric roler ranged from zero to ten according to the variables table.

Secondary

MeasureTime frame
Patients sedation score. Timepoint: during the 2 nd,6th,12th,24th hours after surgey. Method of measurement: to score the patients sedation ramsy sedation score was used.;Nausea and vomiting. Timepoint: during the 2 nd,6th,12th,24th hours after surgey. Method of measurement: The amont of N&V were measured according to N&V score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahram Galiche Chi

Ardabil University of Medical Sciences

Dr.AkhavanAkbari@Gmail.com; Dr.GhaziAhmad@Gmail.com+98 45 3352 2247

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026