The effect of clonidine on the tip shoulder pain and hemodynamic complications of laparoscopy

The effect of oral clonidine on the shoulder tip pain and hemodynamic response of patients undergoing laparoscopic surgeries

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017071117468N4

Enrollment

Registered

2017-08-16

Start date

2017-03-25

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Laparoscopic cholecystectomy. Condition 2: Laparoscopic inguinal hernia repair. Calculus of gallbladder without cholecystitis Inguinal hernia

Interventions

Intervention 1: In control group: Patients received placebo tablets in the same shape of the clonidine tablets and the same times with intervention group. Intervention 2: In intervention group: Patien

Placebo

Treatment - Drugs

In control group: Patients received placebo tablets in the same shape of the clonidine tablets and the same times with intervention group.

In intervention group: Patients received 0.2 mg oral Clonidine (CLONIDINE HCL 0.4MG TAB, Toliddaru, Iran) before induction. Then, other doses of drug (0.2 mg) will prescribe after being awake and 6 ho

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA grades II and III, males and females, adult patients aged 18 to 65 years scheduled Laparoscopic surgeries. Exclusion criteria: Lack of patient consent, history of bronchial asthma, diabetes and hypertension, patients allergic to clonidine, hypertensive and diabetic patients, severe coronary insufficiency, recent myocardial infection, concomitant use of monoamine oxidase inhibitors, tricyclic antidepressants or opioids.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Patient's pain intensity. Timepoint: Just after awaking, 4, 8, 12, 24 hours after operation and time of patient's discharge. Method of measurement: According to VAS rating score.	—

Secondary

Measure	Time frame
Heart rates. Timepoint: Just before prescribing drug and induction, 4, 8, 12, 24 hours after operation and time of patient's discharge. Method of measurement: Will be recorded by Automatic Hemodynamic Monitoring.;Mean arterial blood pressure. Timepoint: Just before prescribing drug and induction, 4, 8, 12, 24 hours after operation and time of patient's discharge. Method of measurement: Will be recorded by Automatic Hemodynamic Monitoring.	—

Measure

Time frame

Heart rates. Timepoint: Just before prescribing drug and induction, 4, 8, 12, 24 hours after operation and time of patient's discharge. Method of measurement: Will be recorded by Automatic Hemodynamic Monitoring.;Mean arterial blood pressure. Timepoint: Just before prescribing drug and induction, 4, 8, 12, 24 hours after operation and time of patient's discharge. Method of measurement: Will be recorded by Automatic Hemodynamic Monitoring.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hamid Mirhosseini

Yazd University of Medical Sciences

Mirhoseini.h@gmail.com+98 35 3624 5956

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026