The effect of selenium on the thyroid nodule

The effect of selenium on the size of thyroid nodules in euthyroid patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170710035001N2

Enrollment

Registered

2018-05-16

Start date

2018-05-05

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

THYROID NODULE. E04.1-E04.9

Interventions

Intervention 1: Intervention group: Edible selenium capsule Use 200 micro grams per day for three months,Manufacturer of the century21 country of America. Intervention 2: Control group: Taking placebo

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: have a thyroid nodule measuring more than 1 cm in size or a multi nodular goiter with a nodule greater than 1 cm These patients should have normal cytology (in FNA thyroid) the serum levels of selenium should be in the normal range

Exclusion criteria

Exclusion criteria: Pregnant women Thyroid nodule diagnosed as suspected or malignant in FNA If the patient is not satisfied with the continuation of the study, selenium intolerance

Design outcomes

Primary

Measure	Time frame
Thyroid nodule size. Timepoint: Before intervention, three months after intervention. Method of measurement: Sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmasoud mohebbi

Mashhad University of Medical Sciences

MohebbiM@mums.ac.ir+98 51 3802 2358

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026