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Changes of Bispectral Index in Ketamine Anesthesia

Comparison of the effect of ketamine with propofol on the bispectral index number in patients who are candidates for elective colorectal surgery in 2024 in Imam Khomeini hospital complex

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170709034978N4
Enrollment
128
Registered
2024-08-25
Start date
2024-09-21
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective colorectal surgeries.

Interventions

Intervention 1: Intervention group: In the intervention group, ketamine is used as an intravenous anesthetic to induce (2-2.5 mg/kg) and maintain (50 mcg/kg/min) anesthesia. For movement relaxation, a

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients calssified as ASA 1&2 who are candidates for elective colorectal surgery with a minimum duration of 2 hours admitted to Mahdi clinic operating room

Exclusion criteria

Exclusion criteria: Two entities of BMI (30) Hypertension Pscychiatric disorders Denial for consent to participate in the study

Design outcomes

Primary

MeasureTime frame
Changes in Bispectral index. Timepoint: Before premedication, before induction, before intubation, after intubation, before 1st surgical stimulation, 5 minutes after 1st surgical stimulation, mean during operation, before reversal of neuromuscular block, before extubation, after extubation. Method of measurement: Depth of anesthesia monitoring device by the method of bispectral index.

Secondary

MeasureTime frame
Recall of anesthesia. Timepoint: After emergence from anesthesia in recovery ward. Method of measurement: Modified Brice questionnare.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Rezaee

Tehran University of Medical Sciences

a_rezaee97@yahoo.com+98 21 6119 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026