Comparison of the effects and side effects of sedation with propofol protocol and midazolam and pethidine protocol in endoscopic patients.

A Clinical trial to Compare the effects of sedation with propofol protocol and midazolam and pethidine protocol on endoscopy's side effects in patients referring for endoscopy

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017070834959N1

Enrollment

266

Registered

2017-11-09

Start date

2017-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Endoscopy under sedation by propofol. Condition 2: Endoscopy under sedation with midazolam and pethidine. - -

Interventions

Intervention group 2: Endoscopy of the patient under sedation with midazolam plus pethidine protocol

Intervention 1: Intervention group 1: Endoscopy of the patient under sedation with propofol protocol. Intervention 2: Intervention group 2: Endoscopy of the patient under sedation with midazolam plus

Treatment - Other

Intervention group 1: Endoscopy of the patient under sedation with propofol protocol

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age above 18y/o; Consciousness; Ability to participate in the gastrointestinal tract endoscopy under sedation. Exclusion criteria: Non-consciousness; allergy to anesthetic drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Duration of the endoscopy. Timepoint: GI endoscopy—from start to finish. Method of measurement: Stopwatch.;Recovery time after endoscopy. Timepoint: After endoscopy. Method of measurement: Stopwatch.;Patient satisfaction after endoscopy. Timepoint: After endoscopy. Method of measurement: Score expressed by the patient.	—

Secondary

Measure	Time frame
Hypoxia. Timepoint: Before intervention and after intervention. Method of measurement: Pulse oximetry.;Cardiac arrhythmia. Timepoint: Before intervention and after intervention. Method of measurement: Heart monitoring.;Blood pressure. Timepoint: Before and after intervention. Method of measurement: Sphygmomanometer.;Nausea. Timepoint: ?After intervention. Method of measurement: Observation.;Vomiting. Timepoint: ?After intervention. Method of measurement: Observation.	—

Measure

Time frame

Hypoxia. Timepoint: Before intervention and after intervention. Method of measurement: Pulse oximetry.;Cardiac arrhythmia. Timepoint: Before intervention and after intervention. Method of measurement: Heart monitoring.;Blood pressure. Timepoint: Before and after intervention. Method of measurement: Sphygmomanometer.;Nausea. Timepoint: ?After intervention. Method of measurement: Observation.;Vomiting. Timepoint: ?After intervention. Method of measurement: Observation.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactJalal Sayyah

Ahvaz Jundishapur University of Medical Sciences

sayyahjalal@gmail.com+98 61 3222 8415

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026