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Study the effect of memantine on acute pain

Study the effect of memantine on acute postoperative pain after elective hysterectomy .

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017070434888N1
Enrollment
60
Registered
2017-11-01
Start date
2017-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: pain. Condition 2: Hysterectomy. Acute pain Acquired absence of genital organ(s)

Interventions

Intervention 1: Memantine, 20 mg oral tablet, one hour before surgery. Intervention 2: placebo.
Treatment - Drugs
Memantine, 20 mg oral tablet, one hour before surgery
placebo

Sponsors

Vice chancellor for research of university of medical sciences of zahedan
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Main criteria for entering the study: patient satisfaction, ages 20 to 70, selective hysterectomy surgery. Main exclusion criteria for the study of liver-renal or cardiac diseases and psychiatric illness that may disturb the patient's assessment, drug addiction or any other psychoactive substance, patient's death, and patient's lack of cooperation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: At recovery and hours 6, 12, 24, 36 and 48 after surgery. Method of measurement: Score measured by VAS criteria.

Secondary

MeasureTime frame
Relaxation. Timepoint: At recovery and hours 6, 12, 24, 36 and 48 after surgery. Method of measurement: Relaxation based on Ramsey's relaxation score.;Drug use Required Patient. Timepoint: Within 48 hours after surgery. Method of measurement: Drug use included in patient file.;Complications (nausea and vomiting). Timepoint: Within 48 hours after surgery. Method of measurement: Ask the patient for the presence or absence of nausea and vomiting.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr asadolah shakeri

university of medical sciences of zahedan

keshtgarsaeed341@yahoo.com+98 54 3329 5571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026