Ventilator associated pneumonia(VAP). Bacterial pneumonia, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group: Patients receive the first dose of probiotics during the first 24 hours of intubation and, until extubation or up to 10 days after the intubation, every 12 hours, o
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: age over than 18 year Length of stay in ICU for more than 5 days
Exclusion criteria
Exclusion criteria: Diarrhea at first visit or 48 hours before admission immune deficiency Regular treatment with probiotics before admission pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of ventilator associated pneumonia(VAP). Timepoint: Up to 15 days after starting probiotics, ventilator-associated pneumonia will be examined. Method of measurement: Daily hematologic examination (CBC and neutrophil count), active phase proteins (CRP or proxlotonin or ferritin) and chest X ray, Based on the American College of Chest Physicians clinical criteria, new or sustained infiltration in the CXR with 2 or 3 of the following findings: fever (.38.58C or ,35.08C), leukocytosis (white bloodcells . 10,000/mm3 or ,3,000/mm3), and purulent sputum. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Farshid Abedi
Birjand University of Medical Sciences
Outcome results
None listed