Comparison of effectiveness of inositol and metformin in infertile women with polycystic ovary syndrome (PCOS)

Comparison of effectiveness of inositol and metformin in infertile women with polycystic ovary syndrome (PCOS) treated with letrozole and gonadotropin

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017070234845N1

Enrollment

Registered

2017-10-02

Start date

2016-03-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovarian syndrome. Polycystic ovarian syndrome

Interventions

group 1, inositol 2 g plus 200 micrograms of folic acid twice daily

group II , 1500 mg of metformin daily plus 200 micrograms of folic acid and group 3, 200 micrograms of folic acid (as a placebo) for three months.

Treatment - Drugs

group II , 1500 mg of metformin daily plus 200 micrograms of folic acid and group 3, 200 micrograms of folic acid (as a placebo) for three months

Eligibility

Sex/Gender

Female

Age

15 Years to 38 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with polycystic ovary syndrome according to Rotterdam criteria; age 15-38 years old. Exclusion criteria: no desire to cooperation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Ovary function. Timepoint: monthly. Method of measurement: Follicole size more than 16 mm.	—

Secondary

Measure	Time frame
Pregnancy. Timepoint: monthly. Method of measurement: pregnancy test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Sajadeh Pourghasem

Hormozgan University of Medical Science

res@hums.ac.ir00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 4, 2026