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The effect of anethum graveolens on pain relief from arthritis

Formulation of traditional preparation of “shevid marham”and a novel topical drug delivery form the essential oil a of Dill (Anethum graveolens) and study of their effect on pain in osteoarthiritis of knee.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170702034861N7
Enrollment
90
Registered
2019-02-27
Start date
2019-02-20
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Make up to one gram twice a day, topically. Intervention 2: novel formulation of extracts and essential oils in a dose of 1 gram twice a day. Intervention 3: Sesame oil is 1 g twice a

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Primary knee osteoarthritis patients aged 40 to 80 Joint pain of osteoarthritis with or without symptoms Radiological Signs of Knee Arthritis Patients of Knee Osteoarthritis according to American Rheumatology Association criteria

Exclusion criteria

Exclusion criteria: Patients with acute phase of knee arthritis Secondary osteoarthritis (such as severe joint trauma and rhomathologic diseases) Inability to keep track of enough Diabetic neuropathy

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 14 day. Method of measurement: The Western Ontario and McMaster Universities Osteoarthritis Index.

Secondary

MeasureTime frame
Percentage of active ingredients. Timepoint: Once. Method of measurement: GC-MASS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSetareh Saei

Kerman University of Medical Science

setareh5307@gmail.com+98 34 3132 5020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026