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Evaluation of clinical and peak flowmetry of nebulized Ketamin in acute asthma attack

Evaluation of clinical and peak flowmetry of nebulized Ketamin in acute asthma attack

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017063015446N10
Enrollment
240
Registered
2017-07-11
Start date
2016-11-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma. Asthma

Interventions

Intervention 1: In the case group, 1 mg / kg of ketamine is inhaled in 1 dose at 0 minuts. Intervention 2: in two group,2.5 mg inhaled albotrol. In 3 doses with a 20 minute interval. Intervention 3:
Treatment - Drugs
In the case group, 1 mg / kg of ketamine is inhaled in 1 dose at 0 minuts
in two group,2.5 mg inhaled albotrol. In 3 doses with a 20 minute interval
In both intervention and control groups. Ipratropium 0.5 mg inhaler with a 20 minute interval in three doses

Sponsors

Ahvaz Jundishapur University Of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: At least 18 years of age and up to 65 years old, patients with complaints of acute shortness of breath have been referred to the emergency department and According to the early symptoms, asthma was diagnosed ( Triad shortness of breath;diffusion wheezing and cough ) Exclusion criteria: Patients with lungs disorder and asthmatic manifestations such as ILD ... Smokers with more than 10packs per year of smoking, history of chronic bronchitis, acute medical problem, coronary artery disease, cardiac arrhythmia, high intracranial pressure, women Pregnant and nebolizer beta-agonist treatment for the past 6 hours, and mild and severe asthma attack are excluded

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
FEV1. Timepoint: At 0,20, 40, 60, 90,minutes Since the beginning of the intervention. Method of measurement: Litre, by spirometry.;Peak Expiratory Flow Rate (PEFR). Timepoint: At 0,20, 40, 60, 90,minutes Since the beginning of the intervention. Method of measurement: Litre, by spirometry.

Secondary

MeasureTime frame
Respiratory rate. Timepoint: Minutes 0, 20, 40, 60and 90 since the beginning of the intervention. Method of measurement: Counting of respiration in one minute.;Pulse rate. Timepoint: Minutes 0, 20, 40, 60and 90 since the beginning of the intervention. Method of measurement: Counting of pulse in one minute.;Blood pressure. Timepoint: Minutes 0, 20, 40, 60and 90 since the beginning of the intervention. Method of measurement: mmHg, by sphygmomanometer.;Blood oxygen saturation levels (SpO2). Timepoint: Minutes 0, 20, 40, 60and 90 since the beginning of the intervention. Method of measurement: Percentage, by pulse oximeter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hassan Motamed

Ahvaz Jundishapor University of Medicial Sciences

motamed-h@ajums.ac.ir+98 61 3374 3079

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026