A comparative effiicacy of two anesthetics in teeth anesthesia

A comparative onset and duration of anesthetic of articaine 4% with epinephrine 1:200000 and lidocaine 2% with epinephrine 1:80000 with AMSA nerve block in anterior and premolar teeth

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017062915782N6

Enrollment

Registered

2017-08-21

Start date

2017-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

local anesthesia. Local anaesthetics

Interventions

Intervention 1: Injection of 0.9 ml Lidocaine 2% with epinephrine 1:80000 with AMSA technique in 60 seconds. Intervention 2: Injection of 0.9 ml Articaine 4% with epinephrine 1:200000 with AMSA techni

Treatment - Drugs

Injection of 0.9 ml Lidocaine 2% with epinephrine 1:80000 with AMSA technique in 60 seconds.

Injection of 0.9 ml Articaine 4% with epinephrine 1:200000 with AMSA technique in 60 seconds.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients between 18 and 65 years; patients with minimum one healthy tooth quadrant of maxilla Exclusion criteria: systemic diseases; pregnancy and lactation; allergy to local anesthetic agents; take any CNS depressants or any medication within the last 24 h; have pulp and preapical disease; using tobacco or any other products

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Duration of anesthesia. Timepoint: every one minutes after injection. Method of measurement: minute-hand clock.;Onset of anesthesia. Timepoint: every one minutes after injection. Method of measurement: minute-hand clock.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPeyman Mehrvarzfar

Tehran Medical Science Branch, Islamic Azad University

P_mehrvarzfar@dentaliau.ac.ir+98 21 8875 9644

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026