Non alcoholic fatty liver. Fatty (change of) liver, not elsewhere classified
Conditions
Interventions
Intervention 1: Control group: Given placebo twice a day for 3 month. Intervention 2: Intervention group: Given Lcarnitine tablet twice a day for 3month.
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to 15 Years
Inclusion criteria
Inclusion criteria: Children with non- alcoholic fatty liver disease Age between 5-15 years old Elevation of liver enzyme more than 40 Unit/Litre Evidence of fatty liver in sonography
Exclusion criteria
Exclusion criteria: Diagnosis of liver disease other than NAFLD such as : Viral hepatitis,Autoimmune hepatitis,Diabetes,Hemochromatosis,Cirrhosis,Infectious disease,Hypothyroidism Consumption of drugs that effect on liver enzyme during last two months Alcohol consumption Discontinuing the study by the patient or his/her family
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurement of serum liver specific enzyme level(Alanine aminotransferase). Timepoint: Three months after treatment initiation with placebo and L-carnitine. Method of measurement: Quantitative measurement of liver transaminase and liver sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assaiment of body mass index. Timepoint: Three months after treatment initiation with placebo and L-carnitine. Method of measurement: Measurement of height and weight and ratio of weight to square of height. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMajid Khademian
Esfahan University of Medical Sciences
Outcome results
None listed