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The efficacy of nasal high frequency ventilation in treatment of neonatal respiratory syndrome

Therapeutic effect of Nasal high frequency ventilation(NHFV) versus nasal continuous positive airway pressure(NCPAP) for respiratory distress syndrome in newborn with birth with more than 1000 gram and more than 30 week of gestational age

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017062734782N1
Enrollment
62
Registered
2017-09-09
Start date
2017-10-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory distress syndrome. Respiratory distress syndrome of newborn

Interventions

Intervention 1: Infants with respiratory distress syndrome according of inclusion criteria randomized to NCPAP (control group) will treat with nasal CPAP shortly after birth. CPAP pressure will consid
Treatment - Devices
Infants with respiratory distress syndrome according of inclusion criteria randomized to NCPAP (control group) will treat with nasal CPAP shortly after birth. CPAP pressure will consider as 6-7 cmH20
Infants with respiratory distress syndrome according of inclusion criteria randomized to NHFV (control group) will treat with nasal high frequency ventilator [Fabian, Acutronic Medical Systems AG, bas

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Months

Inclusion criteria

Inclusion criteria: Inclusion criteria: premature and term neonate; more than 1000 gram and 30 weeks of gestational age; spontaneous breathing; respiratory distress syndrome symptoms required treatment Exclusion criteria: major congenital anomaly; diaphragmatic hernia; cyanotic heart disease; intrauterine growth retardation; asphyxia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The duration of non-invasive support. Timepoint: Every hour. Method of measurement: hourly NICU recorded sheets.—

Secondary

MeasureTime frame
Pulmonary hemorrhage. Timepoint: hourly. Method of measurement: physical exam and chest xray if needed.;Narcotizing enterocolitis (NEC). Timepoint: Daily. Method of measurement: Daily recorded sheets and daily physical exam and abdominal xray if needed.;Intraventricular hemorrhage (IVH). Timepoint: at the 3rd and 7th days after birth. Method of measurement: brain sonography.;Respiratory failure and intubation. Timepoint: continuously every hour during non-invasive respiratory support. Method of measurement: NICU record sheets.;Pnuemothorax. Timepoint: continuously every hour during non-invasive respiratory support. Method of measurement: NICU record sheets.;Chronic lung disease. Timepoint: 4 weeks after birth. Method of measurement: NICU record sheets.;Patent ductus arteriosus. Timepoint: Daily physical exam. Method of measurement: Daily recorded sheets.;Time to full enteral feeding. Timepoint: Daily till full feeding. Method of measurement: Daily recorded sheets.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ahmadreza Abedi

Isfahan University of Medical Sciences

Aabedi58@yahoo.com+98 31 3386 8247

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 21, 2026