Condition 1: . Condition 2: vitamin d deficiency. Condition 3: atrial fibrillation after the surgery. Vitamin D deficiency, unspecified Atrial fibrillation and flutter
Conditions
Interventions
Intervention 1: Intervention group: receiving vitamin d active drug. Intervention 2: Control group: receiving placebo.
Sponsors
isfahan university of medical sciences
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: b) Hypovitaminosis D (serum 25(OH) Vitamin D< 20 ng/ml) c) Written and informed consent to participate in this project CABG indications like trivessel occlusion no emergency intervention needed
Exclusion criteria
Exclusion criteria: e) Hyperparathyroidism (PTH>upper normal limit according to lab reference range) f) Liver failure (any positive past medical history or AST and/or ALT 2 times more than normal upper limit) g) Renal Failure (any positive past medical history or Glomerular filtration rate 30 kg/m2 vitamin d toxicity hypercalcemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of atrial fibrillation after the surgery. Timepoint: till 7 days after the surgery 24 hours in ICU. Method of measurement: electrocardiography.;Number of atrial fibrillation. Timepoint: till 7 days after the surgery 24 hours in ICU. Method of measurement: electrocardiography.;Left ventricular function. Timepoint: before starting taking drugs, before surgery, before discharging from hospital. Method of measurement: echocardiography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Left ventricular function after 1 year. Timepoint: before starting taking drugs, before surgery, before discharge and 1 year after the surgery. Method of measurement: echocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehran Shahzamani
Isfahan University of Medical Sciences
Outcome results
None listed