Aacut ST elevation myocardial infarction. ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction
Conditions
Interventions
Intervention 1: Intervention group: prescribed 180 mg ( two tablet) Ticagrelor orally as a loading dose before stent deployment in cath lab. Intervention 2: Control group: prescribed 600 mg (8 tablet)
Sponsors
Vice chancellor for research of Shahid Rajaiee Heart Center
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: age > 18 years presented with STEMI suitable infarcted related artery for angioplasty patient satisfaction
Exclusion criteria
Exclusion criteria: More than single vessel involvement in angiography unprotected leftmain lesion stent thrombosis presentation with cardiogenic shock history of CVA history of MI contraindication of adenosine High degree AV block TIMI flow < 3 at the end of the angioplasty patient dissatisfaction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intramyocardial resistance. Timepoint: immediately after procedure. Method of measurement: QFR software. | — |
Secondary
| Measure | Time frame |
|---|---|
| Left ventricle ejection fraction. Timepoint: during first 24 hours and 3 month after procedure. Method of measurement: echocardiography.;Wall motion score index. Timepoint: during first 24 hours and 3 month after procedure. Method of measurement: echocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahram Mohebi
Iran University of Medical Sciences
Outcome results
None listed