Effect of prophylactic intracoronary adenosine injection in non ST-elevation myocardial infarction

Effect of prophylactic intracoronary adenosine injection during percutaneous coronary intervention on Thrombolysis In Myocardial Infarction frame count in patients with non ST-elevation myocardial infarction

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170619034621N2

Enrollment

Registered

2020-02-01

Start date

2019-11-22

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non ST elevation myocardial infarction. ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction

Interventions

Intervention 1: intervention group: Adenosine will be used as the vasodilator drug in this group.It will be prescribed intracoronary via well engaged guiding catheter.The dose will be mentioned as fol

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: chest pain or equivalent angina refer to myocardial ischemia past less than 72 hours from onset of symptoms ECG with ST depression or T wave inversion or normal ECG elevated troponin the patients candidate for PCI and their coronary stenosis suitable for stenting age more than 18 years fill out an informed constant form

Exclusion criteria

Exclusion criteria: History of asthma and chronic obstructive pulmonary disease Treatment with dipyridamole life expectancy less than 6 months Cardiogenic shock (sustain SBP<90 mmHg) Post coronary artery bypass graft surgery Atrioventricular block in first ECG ST elevation myocardial infarction History of renal failure ( exception patients underwent hemodialysis) Need for Target vessel revascularization ( TVR ) The coronary artery stenosis will not be suitable for angioplasty Left main lesion or severe 3 vessels disease

Design outcomes

Primary

Measure	Time frame
No/slow flow phenomenon. Timepoint: immediately at the end of the procedure. Method of measurement: TIMI frame count in angiography.	—

Secondary

Measure	Time frame
In hospital major adverse cardiac and cerebral events. Timepoint: during hospitalization. Method of measurement: monitoring.;Period of hospitalization. Timepoint: during hospitalization. Method of measurement: measuring the number of day that patient which hospitalized.;Lethal arrhythmia. Timepoint: during hospitalization. Method of measurement: cardiac monitoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Mozayanimonfared

Shahid Rajaiee Heart Center

a.mozayani@umsha.ac.ir+98 21 23921

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026