Comparing effect of anti fungal therapy with Zataria Multi Flora and Nystatin in treatment of fungous associated with removable prothesis

Comparing effect of anti fungal therapy with Zataria Multi Flora and Nystatin in the treatment of patients with Denture stomatitis type 2 and type 3

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017061834619N1

Enrollment

Registered

2017-09-24

Start date

2017-10-07

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Denture stomatitis. Candidiasis

Interventions

Intervention 1: intervention: drug(Zataria Multi Flora drop-5 cc -4 times in day for 2 weeks- wash the mouth). Intervention 2: control : standard drug(Nyststin suspension- 40 drops-4 times in day for

Treatment - Drugs

intervention: drug(Zataria Multi Flora drop-5 cc -4 times in day for 2 weeks- wash the mouth)

control : standard drug(Nyststin suspension- 40 drops-4 times in day for 2 weeks- wash the mouth )

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria:patients above 18; with Denture stomatitis type 2 and 3 Exclusion criteria: patients with Renal disease; Liver disease; Thyroid disease; Diabet; Xerostomia; hypoparathyroidism; pregnant; brest feeding women; changes in immune system; chemotherapy; radiotherapy; patients who take antibiotics and antifungal drugs within 4 weeks ago

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

Measure	Time frame
How long use removable denture. Timepoint: before intervention. Method of measurement: years-question from patient.;Type of Denture stomatitis. Timepoint: before intervention. Method of measurement: type 2,3- visual.;How clean the removable denture. Timepoint: before intervention. Method of measurement: water/brush/cleaning agent- question from patient.;Freqency of cleaning removable denture. Timepoint: before intervention. Method of measurement: 0/1/2/3 and more than 3 in week- question from patient.;Remove of removable denture in night. Timepoint: before intervention. Method of measurement: yes/no -question from patient.	—

Measure

Time frame

How long use removable denture. Timepoint: before intervention. Method of measurement: years-question from patient.;Type of Denture stomatitis. Timepoint: before intervention. Method of measurement: type 2,3- visual.;How clean the removable denture. Timepoint: before intervention. Method of measurement: water/brush/cleaning agent- question from patient.;Freqency of cleaning removable denture. Timepoint: before intervention. Method of measurement: 0/1/2/3 and more than 3 in week- question from patient.;Remove of removable denture in night. Timepoint: before intervention. Method of measurement: yes/no -question from patient.

—

Primary

Measure	Time frame
Count of cloni. Timepoint: before intervention-2 weeks after intervention. Method of measurement: CFU with microbiological measurment.;Erythem. Timepoint: before intervention-2 weeks after intervention. Method of measurement: mm2- with grid.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElnaz Gonoodi

Azad Islamic University of Tehran- school of Dentistry

t_farrokhnia@dentaliau.ac.irelnazgonoudi@gmail.com+98 2122

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026