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Effects of fluoride and laser on streptococcus mutans

A clinical trial on the effects of topical fluoride, laser diode, and their combined application on the number of streptococcus mutans in saliva of 7- to 10-year-old children

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017061817756N20
Enrollment
36
Registered
2017-07-09
Start date
2017-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Streptococcus mutans. Streptococcus, group B, as the cause of diseases classified to other chapters

Interventions

Intervention 1: Intervention Group 2 (Fluoride Group): The members will receive fluoride therapy on all tooth surfaces using sodium fluoride varnish. Intervention 2: Intervention Group 3 (Fluoride pl
Prevention
Intervention Group 2 (Fluoride Group): The members will receive fluoride therapy on all tooth surfaces using sodium fluoride varnish.
Intervention Group 3 (Fluoride plus Diode Laser): The members will receive fluoride therapy and immediately after it, they will have 940 nanometer wavelength diode laser for 30 seconds on the buccal,
Intervention Group 1 (Laser Diode): The members will receive 940 nanometer wavelength diode laser for 30 seconds on the buccal, lingual, palatal and dorsal surfaces.

Sponsors

Vice-Chancellery for Research and Technology of Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 10 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children aged 7 to 10 years without dental caries; non-use of antibiotics prior to visit; lack of medical history; lack of either systemic or topical fluoride use (excluding toothpaste). Exclusion criteria: Unwillingness to cooperate in the study; not being in the mixed dentition stage.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Streptococcus mutans level. Timepoint: Before and 24 hours after intervention. Method of measurement: Colony forming units.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoome Saeidirad

Birjand University of Medical Sciences

rad.masoome71@gmail.com+98 56 3239 5680

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026