Effect of Pulsed Dye Laser and topical sirolimus for treatment of port wine stain

Comparison of the Effectiveness of PDL laser with or without topical sirolimus 0.2% for treatment of portwine stain

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170617034590N2

Enrollment

Registered

2018-09-07

Start date

2017-10-23

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

port-wine stain. Congenital non-neoplastic naevus

Interventions

Intervention 1: Intervention/control 1: PDL on months 0, 2, 4 and 6 in whole of lesion(control and treatment site). Intervention 2: Intervention 2 :using sirulimos in one part of lesion. Intervention

Eligibility

Sex/Gender

All

Age

1 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1 to 50 years old patient with portwine stain Not received any treatments during the last 6 months

Exclusion criteria

Exclusion criteria: Being pregnant, actively trying to become pregnant or breast-feeding previous history of malignancy Having hypersensitivity or contraindication to the treatments

Design outcomes

Primary

Measure	Time frame
Reducing erythem in lesion. Timepoint: 2months after last treatment. Method of measurement: photographs taken on months 0 and 2 months after last treatment and analyze with visioface device( to determine of reducing erythma in quantity ).	—

Secondary

Measure	Time frame
Patient's satisfaction. Timepoint: At the end of the study. Method of measurement: Patient Global Assesment (asking them to score 0 _10).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid-Reza Mahmoudi

Razi Hospital

hr_mahmoody@yahoo.com+98 21 5561 8989

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026