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Vitamin C and Percutaneous Coronary Intervention

Effectiveness of Intravenous and intracoronary Vitamin C for the Prevention of Periprocedural Myocardial Injury And Contrast-Induced Acute Kidney Injury in Patients Undergoing Primary Percutaneous Coronary Intervention.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201706168698N21
Enrollment
110
Registered
2017-08-20
Start date
2016-05-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction. Acute transmural myocardial infarction of unspecified site Transmural myocardial infarction NOS

Interventions

Intervention 1: Intervention group: Moreover the routine treatment before primary PCI and stenting of culprit lesion 3 gram of intravenus vitamin C bolus and after stenting 96 mg intracoronary will be
Treatment - Drugs
Intervention group: Moreover the routine treatment before primary PCI and stenting of culprit lesion 3 gram of intravenus vitamin C bolus and after stenting 96 mg intracoronary will be inject.
Control group: routine treatment will be do.

Sponsors

Vice Chancellor for research,Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Subjects (men or women) at least 18 years and less than 80 years of age; Ischemic discomfort = 20 min and 4.0 mg/dl).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Myocardial infarction. Timepoint: before intervention. Method of measurement: clinical history and ECG.;Troponin I. Timepoint: before and 6, 18 hour after PCI. Method of measurement: ELISA.;Creatine Kinase-MB. Timepoint: before and 6,18 hour after PCI. Method of measurement: spectrophotometry.;NGAL. Timepoint: before and 6 hour after PCI. Method of measurement: ELISA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzita Haj Hossein Talasaz

Tehran Heart Center

atalasaz@razi.tums.ac.ir+98 21 8802 9600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026