The effect of Amantadin on the level of consciousness in patients with traumatic brain injury with an average level of consciousness on arrival at the Golestan hospital in 1395 and 1396

The effect of Amantadin and placebo(Acetaminophen) on the level of consciousness in patients with traumatic brain injury with an average level of consciousness

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017061634573N1

Enrollment

Registered

2017-08-16

Start date

2016-03-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic brain injury. Diffuse brain injury

Interventions

Drug therapy in the control group (Amantadine tablets 200 mg) and case group (Acetaminophen200).

Treatment - Drugs

Drug therapy in the control group (Amantadine tablets 200 mg) and case group (Acetaminophen200)

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: inclusion:level of consciousness between 9 and 13 ; arrived a day gavage ; absence of kidney damage and other diseases ; are not sensitive to amantadine ; no pregnancy, no injury ;having age between 18 to 60 -Exclusion criteria: expair patient during the study ; drug toxicity ; cardiac arrest ; respiratory and renal damage in patients; with surgical complications and seizure ; of clotting problems ; maxillofacial trauma

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Level of consciousness. Timepoint: after arrival at the unit-one week ?two weeks ? after starting the drug. Method of measurement: Glasgow Coma Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeynab Kord

Ahvaz Jundishapoor University of Medical Sciences

bahare.kord132@gmail.com+98 61 3374 3701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026