Drug resistant epilepsy. Epilepsy and recurrent seizure
Conditions
Interventions
Intervention group: children with Drug resistant epilepsy that are received oral probiotic supplementation as daily with 2 month. The probiotic supplement is Prokid from Gostaresh Milad Farmed Co., wh
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Years to 15 Years
Inclusion criteria
Inclusion criteria: Patients with a diagnosis of refractory epilepsy. Patients are between 3 and 15 years old. children who have a medical record with a medical doctor and have been referred to the pediatric neurosurgery clinic of Shahid Beheshti Hospital for treatment. They have had at least one seizure in the past three months.
Exclusion criteria
Exclusion criteria: Children that the cause of their seizures are secondary such as electrolyte imbalances Children with underlying, genetic or progressive brain diseases. Children who have had probiotic use for one month before the study. Children who take antibiotics with any reason for one month before the study. Children who take any immunosuppressant medication with any reason for one month before the study. Children who take any vitamin or mineral supplement except vitamin D
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seizure frequency. Timepoint: before and after probiotic treatment. Method of measurement: asking frequency of seizure frequency. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood indices(Sodium- calcium - potassium - magnesium - hepatic enzymes including alkaline phosphatase, AST and ALT- bilirubin - creatinin). Timepoint: before and after. Method of measurement: Measurement of venous blood sample. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Ahmad Talebian
Kashan University of Medical Sciences
Outcome results
None listed