Melatonin in women with endometriosis

Effect of Melatonin on pelvic pain relief in women with endometriosis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170612034489N2

Enrollment

Registered

2018-05-21

Start date

2639-08-21

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis of uterus. Endometriosis

Interventions

Intervention 1: Intervention group: Melatonin 5 mg for 8 weeks. Intervention 2: Control group: will take placebo with the same identical characteristics as melatonin for the same duration.

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-45 years old that have proven endometriosis associated chronic pelvic pain for last 6 months Patient with menstural cycle 21-35 days Patients with VAS score>7

Exclusion criteria

Exclusion criteria: Patients who had substance and alchohol use in past 6 months Patients were undergoing hormonal therapy in past 3 months

Design outcomes

Primary

Measure	Time frame
Pelvic pain. Timepoint: Before and after 8 week of intervention. Method of measurement: A Visual Analogue Scale.	—

Secondary

Measure	Time frame
Use of analgesic mefenamic acid. Timepoint: Before and after 8 week of intervention. Method of measurement: Health records.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahla Chaichian

Islamic Azad University

Shchaichian@gmail.com+98 21 2264 8065

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026