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The therapeutic effect of Glucuronic acid in breast cancer patients

Evaluation of the effect of Glucuronic acid on processing of breast cancer disease

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017061113739N9
Enrollment
36
Registered
2017-06-14
Start date
2017-07-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Breast Cancer. Condition 2: Breast Cancer. Condition 3: Breast Cancer. Condition 4: Breast Cancer. Condition 5: Breast Cancer. Condition 6: Breast Cancer. Condition 7: Breast Cancer. Condition 8: Breast Cancer. Malignant neoplasm: overlapping lesion of breast Malignant neoplasm: upper-inner quadrant of breast Malignant neoplasm: lower-inner quadrant of breast Malignant neoplasm: upper-outer quadrant of breast Malignant neoplasm: lower-outer quadrant of breast Malignant neoplas

Interventions

Intervention 1: The intervention group will receive 1500 mg/day (three 500 mg tablets/day) of Glucuronic acid orally for 12 weeks. The Glucuronic acid produced from the decomposition of Alginate powde
Treatment - Drugs
Control group will receive of conventional drugs orally for 12 weeks.
The intervention group will receive 1500 mg/day (three 500 mg tablets/day) of Glucuronic acid orally for 12 weeks. The Glucuronic acid produced from the decomposition of Alginate powder (a safe, natur

Sponsors

Vice-Chancellor for Research, Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
65 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 30-60 years old patients, Diagnosed with breast cancer according to American College of oncology Diagnostic Criteria after the initial visit by a specialist in cancer surgery and parameters CEA, CA15.3, CBC and sonography, Each patient must sign written informed consent. Exclusion Criteria: History of fever and Infectious diseases, Positive pregnancy test or Lactation, Other collagen- vascular and auto immune diseases, Patients have enrolled another clinical trial study within last 4 weeks, Other concomitant diseases (Hepatic, renal, haematological, gastrointestinal, endocrine, cardiovascular, pulmonary, neurological or cerebral disease).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Feel the mass and tenacity in breast. Timepoint: At baseline and after 12 weeks of treatment. Method of measurement: Examination by specialist.

Secondary

MeasureTime frame
Tumor size. Timepoint: At baseline and after 12 weeks of treatment. Method of measurement: Sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Abbas Mirshafiey

Department of pathobiology, School of Public Health, Tehran University of Medical Sciences

mirshafiey@tums.ac.ir+98 21 8895 4913

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026