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The Effect of L-Carnitine on Inflammaton Post Cardiac Surgery

Potential effect of L-Carnitine on inflmmatory biomarkers post cardiac artery bypass graft surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201706108698N20
Enrollment
100
Registered
2017-07-11
Start date
2017-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Heart Disease. Angina pectoris

Interventions

Intervention 1: Intervention 1: L-carnitine 3 g every 8 hours from 2 days before to 2 days after surgery. Intervention 2: Intervention 2: No additional drug would be prescribed.
Treatment - Drugs
Intervention 1: L-carnitine 3 g every 8 hours from 2 days before to 2 days after surgery
Intervention 2: No additional drug would be prescribed.

Sponsors

Vice chancellor for research, Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patients who are a candidate for Coronary artery bypass graft surgery in Tehran Heart Center; Exclusion criteria: Valvular surgery; History of seizure; History of hypersensitivity reaction to l-carnitine; Chronic liver failure (Liver enzymes more than 3 times of upper limit of normal); Chronic kidney disease (Stage IV and V); Hypothyroidism

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
NLR. Timepoint: Before and 48 hours post surgery. Method of measurement: CBC.;PLR. Timepoint: Before and 48 hours post surgery. Method of measurement: CBC.;Hs-CRP. Timepoint: Before and 48 hours post surgery. Method of measurement: Elisa kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzita Hajhossein Talasaz

Tehran University Of Medical Science

a-talasaz@tums.ac.ir+98 21 8802 9242

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026