obesity. Obesity due to excess calories
Conditions
Interventions
Intervention 1: Intervention group 1: acupuncture, 3 times per week + 4 tablets of 160 mg Perforan (Goldaru company) + life style modification for 6 weeks. Intervention 2: Intervention group 2: acupun
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Appetite score more than 5 according to visual analogue scale Body mass index between 24.9 to 39.9 Women 18 years old to pre-menopause; men 18 to 60 years old Failure to life style modification alone "Liver qi stagnation" syndrome according to Chinese Medicine syndrome differentiation
Exclusion criteria
Exclusion criteria: Hypothyroidism, Cushing's syndrome, cancer, liver or kidney failure Using drugs effective on appetite, weight and metabolism in the previous month Using drugs that interfere with Hypericum perforatum such as protease inhibitors, amiodarone, anticoagulants, cyclophosphamide, cyclosporine, monoamine oxidase inhibitors, phenytoin, tacrolimus, tamoxifen and trazodone drug Drug abuse or alcoholism Breast-feeding, pregnancy or planning a pregnancy during the next two months Having pacemaker or any other metal device inside the body due to the use of electroacupuncture and Bioelectrical Impedance Analyzer disability to do recommended physical activity Allergy to Hypericum perforatum or metal Coagulation disorders History of receiving acupuncture
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma nesfatin-1. Timepoint: Before intervention, Sixth week. Method of measurement: Laboratory: ELISA.;Appetite score. Timepoint: Before intervention, weeks 2, 4, 6, 24. Method of measurement: Visual Analogue Scale.;Body Mass Index. Timepoint: Before intervention, weeks 2, 6, 24. Method of measurement: Using the bioelectrical impedance analyzer; kg/m2. | — |
Secondary
| Measure | Time frame |
|---|---|
| Waist circumference. Timepoint: Before intervention, weeks 2, 6, 24. Method of measurement: Using a tape measure; centimeters.;Hip circumference. Timepoint: Before intervention, weeks 2, 6, 24. Method of measurement: Using a tape measure; centimeters.;Body composition. Timepoint: Before intervention, weeks 2, 6. Method of measurement: Using the bioelectrical impedance analyzer.;Lipid profile. Timepoint: Before intervention, week 6. Method of measurement: Laboratory.;Liver enzymes. Timepoint: Before intervention, week 6. Method of measurement: Laboratory.;Blood glucose level. Timepoint: Before intervention, week 6. Method of measurement: Laboratory.;Adverse events. Timepoint: During the study period within 48 to 72 hours of incidence; week 6. Method of measurement: Study checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Monirsadat Sahebkar Khorasani
School of Traditional and Complementary Medicine
Outcome results
None listed