Evaluating the effect of propolis tablets on chemotherapy induced oral mucositis

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017060933722N2

Enrollment

Registered

2017-07-02

Start date

2017-07-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chemotherapy induced oral mucositis. oral mucositis ( drug induced )

Interventions

Intervention 1: Intervention group: administration of oral propolis tablet 50mg,twice a day(BID) up to 21 days. Intervention 2: Control group: receives pelacebo.

Treatment - Drugs

Placebo

Intervention group: administration of oral propolis tablet 50mg,twice a day(BID) up to 21 days.

Control group: receives pelacebo

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with colon cancer who receive Folfox chemotherapy regimen with oral mucositis at grade 0 level from WHO indice. Exclusion criteria: Chronic liver failure(stage2,3); Chronic kidney disease(stage4,5); Oral signs and symptoms of any type of allergy and sensitivity to honey and propolis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of oral mucositis. Timepoint: once a week (weekly ). Method of measurement: according to WHO and OMAS indices.	—

Secondary

Measure	Time frame
_. Timepoint: _. Method of measurement: _.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Ghodrati

Sari Dentistry College

dr.parisaghodrati@gmail.com+98 11 3324 4014

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026