Burn pruritus. Other pruritus
Conditions
Interventions
Intervention 1: Intervention group:Intervention group (curcumin recipient) includes 50 patients who will receive two capsules of curcumin ( 40mg activing redient in each capsule ) daily by mouth for 3
Sponsors
Ardabil University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age over 18 years ; Having itching after burn injury ; Ability to understand and sign consent form
Exclusion criteria
Exclusion criteria: Other causes of pruritus including renal failure ; Pregnancy; presence of any chronic active, uncontrolled or severe inflammatory disease ( such as autoimmune diseases, connective tissue disease, malignancy, HIV, liver disease and pulmonary disease) ;Breastfeeding ; involvement in other clinical trials ; malabsorption syndrome ; Bleeding disorders ( Including coagulopathies) or high risk for bleeding ;intake of a curcumin supplement or other supplements that affecting itching such as omega_3 in the recent month ; Intolerance or allergy to curcumin ; Receiving drugs that have an effect on inflammatory factors ( sach as corticosteroids or other immunosuppressive drugs, non-steroidal anti-inflammatory drugs, pentoxifylline) in the recent 6 weeks; Use of warfarin ; Abuse of alcohol and other substances that cause dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pruritus score. Timepoint: Before starting the intervention, Six weeks after the intervention and at the end of the intervention period. Method of measurement: Standard questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: Before starting the intervention, Six weeks after the intervention and at the end of the intervention. Method of measurement: Standard questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAfshin Gharekhani
Tabriz University of Medical Sciences
Outcome results
None listed