Efficacy of smelling peppermint essential oil on patients with nausea referred to emergency department of Sina Hospital

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170609034406N6

Enrollment

168

Registered

2020-09-23

Start date

2019-10-30

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: nausea. Condition 2: vomiting. Condition 3: pain. Condition 4: Duration of being in the emergency department. Condition 5: Patient satisfaction at discharge from emergency ward. Nausea and vomiting Nausea and vomiting Pain, unspecified

Interventions

Intervention 1: Intervention group: The first treatment group consists of 56 patients receiving inhaled peppermint essential oil 3 times and oral placebo (which apart from the active ingredient,were s

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Ability to understand and sign a consent form self-reported nausea severity of 3 or greater on a verbal numeric response scale (range 0 to 10)

Exclusion criteria

Exclusion criteria: known allergy to peppermint essential oil inability to inhale through the nares ( include rhinitis) recent intake of antivomiting medications including Ondansetron, Metoclopramide, Granisetron, Domperidone clinical suspicion for serotonin syndrome pregnancy Changing the state of consciousness so as to prevent the understanding and signing of the informed consent form

Design outcomes

Primary

Measure	Time frame
Nausea score. Timepoint: Immediately before intervention. 5?10?20?30?60 minutes after the intervention. Method of measurement: Verbal Numeric Scale.;Vomiting frequency. Timepoint: Immediately before intervention. 5?10?20?30?60 minutes after the intervention. Method of measurement: Standard questionnaire.;Pain score. Timepoint: Immediately before intervention. 5?10?20?30?60 minutes after the intervention. Method of measurement: Verbal Numeric Scale.	—

Measure

Time frame

Nausea score. Timepoint: Immediately before intervention. 5?10?20?30?60 minutes after the intervention. Method of measurement: Verbal Numeric Scale.;Vomiting frequency. Timepoint: Immediately before intervention. 5?10?20?30?60 minutes after the intervention. Method of measurement: Standard questionnaire.;Pain score. Timepoint: Immediately before intervention. 5?10?20?30?60 minutes after the intervention. Method of measurement: Verbal Numeric Scale.

—

Secondary

Measure	Time frame
Duration of being in the emergency department. Timepoint: after the intervention. Method of measurement: previously designed checklist for recording the time.;Patient satisfaction at discharge from emergency ward. Timepoint: after the intervention. Method of measurement: previously designed checklist for recording patient satisfaction.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Gharekhani

Tabriz University of Medical Sciences

gharekhania@tbzmed.ac.ir+98 41 3230 5351

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026