Comparison the antiemetic effect of metoclopramide and ondansetron in patients with minor head trauma

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170609034403N3

Enrollment

Registered

2018-04-15

Start date

2018-03-21

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Minor head trauma. Commotio cerebri

Interventions

Intervention 1: Intervention group: 4 mg ondansetron. Intervention 2: Intervention group: 10 mg metoclopramide. Intervention 3: Control group: without drug.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: minor head trauma with nausea and vomiting normal brain CT scan GCS=15 head trauma in the first 24 hours

Exclusion criteria

Exclusion criteria: multiple trauma chronic disease hypersensitivity to metoclopramide and ondansetron

Design outcomes

Primary

Measure	Time frame
Decrease in nausea and vomiting. Timepoint: befor drug administration, 15 and 30 minutes after drug administration. Method of measurement: Qualitative.	—

Secondary

Measure	Time frame
Satisfaction of treatment. Timepoint: 15 and 30 minutes after drug administration. Method of measurement: Qualitative.;Adverse effects. Timepoint: 15 and 30 minutes after drug administration. Method of measurement: Qualitative.;Need for rescue medication. Timepoint: 15 and 30 minutes after drug administration. Method of measurement: Qualitative.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamideh Feiz Disfani

Mashhad University of Medical Sciences

Feyzh@mums.ac.ir+98 51 3123 4566

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026