Parkinson's disease. Parkinson's disease
Conditions
Interventions
Intervention 1: Intervention group: Patients will take an oral capsule containing 30 mg of crocin in the morning and evening for 8 weeks. Granules containing crocin were obtained from Sami Saz Pharmac
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Idiopathic Parkinson's patients Age 30 to 80 years No change in diet, medication and supplements during 8 weeks They declare their agreement to participate in the clinical trial through a written consent form
Exclusion criteria
Exclusion criteria: Patients with a history of saffron allergy Patients with severe episodes of wearing off Consumers of saffron more than 1 gram per day Taking warfarin, monoamine oxidase inhibitors Pregnant and lactating patients Liver disease Occurrence of urticaria complications; skin itching; Nausea and vomiting and dizziness Patients with severe Hoehn and Yahr stage 5 Parkinson's disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unified Parkinson's Disease Rating Scale (UPDRS). Timepoint: At the beginning and eight weeks after the start of the study. Method of measurement: Unified Parkinson's Disease Rating Scale (UPDRS) Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Malondialdehyde reduction in blood (oxidative stress biomarker). Timepoint: The beginning of the study and the end of the study. Method of measurement: Spectrophotometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHadi Esmaily
Shahid Beheshti University of Medical Sciences
Outcome results
None listed